ABSTRACT
Background: Cutaneous calcifications or calcinosis cutis is an interesting lesion, wherein the skin, soft tissues and in the walls of small/medium sized veins, arteries. The aim of the present study is to evaluate the calcinosis cutis or cutaneous calcification prevalence and also its correlation with age, sex, site of the lesion, clinical features and histopathological findings. Methods: A 5 years prospective study was on 40 patients suspected to have calcinosis cutis. Surgical excision of skin lesions was also performed to do the histopathological study. Results: Women presented with lesions around the waist commonly. Males presented with lesions at different sites like over dorsum of legs and fore arm most commonly. Out of 40 cutaneous calcifications, 14 (35%) were Asymptomatic, 12 (30%) were painless papules/nodules, 8 (20%) were ulceration with or without discharge, 6 (15%) were painful papules/nodules. Conclusion: As the Cutaneous calcifications were mostly asymptomatic or painless, need to evaluate the carefully and treat if there is any underlying pathologies. Calcinosis cutis individuals should be educate and counsel regarding underlying pathologies and treatment.
ABSTRACT
Dengue is an acute infectious disease of viral etiology. It is probably one of the most important arthropod borne viral disease in terms of human morbidity and mortality. The spectrum of disease ranges from self-limited dengue fever to more severe forms of dengue hemorrhagic fever (DHF) or dengue shock syndrome (DSS). Laboratory diagnosis of dengue virus infection mainly depends on detection of virus specific antibodies. The aim of the study was to correlate the serological results with clinical presentation in patients with a diagnosis of dengue. Eleven out of 15 (73.3%) patients with DHF and DSS had secondary antibody response and mortality was 100% in these patients.